منابع مشابه
Novel Targeted Therapies in Ovarian Cancer
Background: Traditional management of women with advanced ovarian cancer with surgery and chemotherapy provides limited duration of survival. Targeting specific pathways in angiogenesis or DNA repair may provide therapeutic benefit. Results: In this manuscript, we review the use of various compounds including antibodies that target specific growth factors receptors or ligands for receptors as w...
متن کاملTargeted Therapies in Epithelial Ovarian Cancer
Molecularly targeted therapy is relatively new to ovarian cancer despite the unquestionable success with these agents in other solid tumours such as breast and colorectal cancer. Advanced ovarian cancer is chemosensitive and patients can survive several years on treatment. However chemotherapy diminishes in efficacy over time whilst toxicities persist. Newer biological agents that target explic...
متن کاملTargeted Therapies in Epithelial Ovarian Cancer
Epithelial ovarian cancer remains a major women's health problem due to its high lethality. Despite great efforts to develop effective prevention and early detection strategies, most patients are still diagnosed at advanced stages of disease. This pattern of late presentation has resulted in significant challenges in terms of designing effective therapies to achieve long-term cure. One potentia...
متن کاملOvarian cancer: emerging molecular-targeted therapies
With about 22,000 new cases estimated in 2012 in the US and 15,500 related deaths, ovarian cancer is a heterogeneous and aggressive disease. Even though most of patients are sensitive to chemotherapy treatment following surgery, recurring disease is almost always lethal, and only about 30% of the women affected will be cured. Thanks to a better understanding of the molecular mechanisms underlyi...
متن کاملAnal fissures associated with targeted therapies in ovarian cancer.
Although ovarian cancer remains a leading cause of gynecologic cancer death, targeted therapies are improving patient outcomes. Anal fissures are a side effect of targeted therapies that can disrupt or stop treatment regimens. Diagnosis and management of anal fissures by advanced practice nurses are crucial for maintaining the quality of life of patients with ovarian cancer.
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ژورنال
عنوان ژورنال: Journal of Cancer Science & Therapy
سال: 2014
ISSN: 1948-5956
DOI: 10.4172/1948-5956.1000293